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CCS Publications  2023

  • Zwicklhuber, J., Kocher, T., Liemberger, B., Hainzl, S., Bischof, J., Strunk, D., Raninger, A.M., Gratz, I., Wally, V., Guttmann-Gruber, C., Hofbauer, J.P., Bauer, J.W., and Koller, U. (2023). A Novel Fluorescence-Based Screen of Gene Editing Molecules for Junctional Epidermolysis Bullosa. Int. J. Mol. Sci. 24. 10.3390/ijms24065197.

  • Zhao, X., Yang, M., Fan, J., Wang, M., Wang, Y., Qin, N., Zhu, M., Jiang, Y., Gorlova, O.Y., Gorlov, I.P., Albanes, D., Lam, S., Tardon, A., Chen, C., Goodman, G.E., Bojesen, S.E., Landi, M.T., Johansson, M., Risch, A., Wichmann, H.E., Bickeboller, H., Christiani, D.C., Rennert, G., Arnold, S.M., Brennan, P., Field, J.K., Shete, S., Le Marchand, L., Liu, G., Hung, R.J., Andrew, A.S., Kiemeney, L.A., Zienolddiny, S., Grankvist, K., Johansson, M., Caporaso, N.E., Woll, P.J., Lazarus, P., Schabath, M.B., Aldrich, M.C., Patel, A.V., Davies, M.P.A., Ma, H., Jin, G., Hu, Z., Amos, C.I., Shen, H., and Dai, J. (2023). Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. Cancer. 10.1002/cncr.35130.

  • Wessler, S., and Posselt, G. (2023). Bacterial Proteases in Helicobacter pylori Infections and Gastric Disease. Curr. Top. Microbiol. Immunol. 444, 259-277. 10.1007/978-3-031-47331-9_10.

  • Urwanisch, L., Unger, M.S., Sieberer, H., Dang, H.H., Neuper, T., Regl, C., Vetter, J., Schaller, S., Winkler, S.M., Kerschbamer, E., Weichenberger, C.X., Krenn, P.W., Luciano, M., Pleyer, L., Greil, R., Huber, C.G., Aberger, F., and Horejs-Hoeck, J. (2023). The Class IIA Histone Deacetylase (HDAC) Inhibitor TMP269 Downregulates Ribosomal Proteins and Has Anti-Proliferative and Pro-Apoptotic Effects on AML Cells. Cancers (Basel) 15. 10.3390/cancers15041039.

  • Shi, J., Shiraishi, K., Choi, J., Matsuo, K., Chen, T.Y., Dai, J., Hung, R.J., Chen, K., Shu, X.O., Kim, Y.T., Landi, M.T., Lin, D., Zheng, W., Yin, Z., Zhou, B., Song, B., Wang, J., Seow, W.J., Song, L., Chang, I.S., Hu, W., Chien, L.H., Cai, Q., Hong, Y.C., Kim, H.N., Wu, Y.L., Wong, M.P., Richardson, B.D., Funderburk, K.M., Li, S., Zhang, T., Breeze, C., Wang, Z., Blechter, B., Bassig, B.A., Kim, J.H., Albanes, D., Wong, J.Y.Y., Shin, M.H., Chung, L.P., Yang, Y., An, S.J., Zheng, H., Yatabe, Y., Zhang, X.C., Kim, Y.C., Caporaso, N.E., Chang, J., Ho, J.C.M., Kubo, M., Daigo, Y., Song, M., Momozawa, Y., Kamatani, Y., Kobayashi, M., Okubo, K., Honda, T., Hosgood, D.H., Kunitoh, H., Patel, H., Watanabe, S.I., Miyagi, Y., Nakayama, H., Matsumoto, S., Horinouchi, H., Tsuboi, M., Hamamoto, R., Goto, K., Ohe, Y., Takahashi, A., Goto, A., Minamiya, Y., Hara, M., Nishida, Y., Takeuchi, K., Wakai, K., Matsuda, K., Murakami, Y., Shimizu, K., Suzuki, H., Saito, M., Ohtaki, Y., Tanaka, K., Wu, T., Wei, F., Dai, H., Machiela, M.J., Su, J., Kim, Y.H., Oh, I.J., Lee, V.H.F., Chang, G.C., Tsai, Y.H., Chen, K.Y., Huang, M.S., Su, W.C., Chen, Y.M., Seow, A., Park, J.Y., Kweon, S.S., Chen, K.C., Gao, Y.T., Qian, B., Wu, C., Lu, D., Liu, J., Schwartz, A.G., Houlston, R., Spitz, M.R., Gorlov, I.P., Wu, X., Yang, P., Lam, S., Tardon, A., Chen, C., Bojesen, S.E., Johansson, M., Risch, A., Bickeboller, H., Ji, B.T., Wichmann, H.E., Christiani, D.C., Rennert, G., Arnold, S., Brennan, P., McKay, J., Field, J.K., Shete, S.S., Le Marchand, L., Liu, G., Andrew, A., Kiemeney, L.A., Zienolddiny-Narui, S., Grankvist, K., Johansson, M., Cox, A., Taylor, F., Yuan, J.M., Lazarus, P., Schabath, M.B., Aldrich, M.C., Jeon, H.S., Jiang, S.S., Sung, J.S., Chen, C.H., Hsiao, C.F., Jung, Y.J., Guo, H., Hu, Z., Burdett, L., Yeager, M., Hutchinson, A., Hicks, B., Liu, J., Zhu, B., Berndt, S.I., Wu, W., Wang, J., Li, Y., Choi, J.E., Park, K.H., Sung, S.W., Liu, L., Kang, C.H., Wang, W.C., Xu, J., Guan, P., Tan, W., Yu, C.J., Yang, G., Sihoe, A.D.L., Chen, Y., Choi, Y.Y., Kim, J.S., Yoon, H.I., Park, I.K., Xu, P., He, Q., Wang, C.L., Hung, H.H., Vermeulen, R.C.H., Cheng, I., Wu, J., Lim, W.Y., Tsai, F.Y., Chan, J.K.C., Li, J., Chen, H., Lin, H.C., Jin, L., Liu, J., Sawada, N., Yamaji, T., Wyatt, K., Li, S.A., Ma, H., Zhu, M., Wang, Z., Cheng, S., Li, X., Ren, Y., Chao, A., Iwasaki, M., Zhu, J., Jiang, G., Fei, K., Wu, G., Chen, C.Y., Chen, C.J., Yang, P.C., Yu, J., Stevens, V.L., Fraumeni, J.F., Jr., Chatterjee, N., Gorlova, O.Y., Hsiung, C.A., Amos, C.I., Shen, H., Chanock, S.J., Rothman, N., Kohno, T., and Lan, Q. (2023). Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population. Nat Commun 14, 3043. 10.1038/s41467-023-38196-z.

  • Pencik, J., Philippe, C., Schlederer, M., Atas, E., Pecoraro, M., Grund-Groschke, S., Li, W.J., Tracz, A., Heidegger, I., Lagger, S., Trachtova, K., Oberhuber, M., Heitzer, E., Aksoy, O., Neubauer, H.A., Wingelhofer, B., Orlova, A., Witzeneder, N., Dillinger, T., Redl, E., Greiner, G., D'Andrea, D., Ostman, J.R., Tangermann, S., Hermanova, I., Schafer, G., Sternberg, F., Pohl, E.E., Sternberg, C., Varady, A., Horvath, J., Stoiber, D., Malcolm, T.I., Turner, S.D., Parkes, E.E., Hantusch, B., Egger, G., Rose-John, S., Poli, V., Jain, S., Armstrong, C.W.D., Hoermann, G., Goffin, V., Aberger, F., Moriggl, R., Carracedo, A., McKinney, C., Kennedy, R.D., Klocker, H., Speicher, M.R., Tang, D.G., Moazzami, A.A., Heery, D.M., Hacker, M., and Kenner, L. (2023). STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway. Mol. Cancer 22, 133. 10.1186/s12943-023-01825-8.

  • Lara-Astiaso, D., Goni-Salaverri, A., Mendieta-Esteban, J., Narayan, N., Del Valle, C., Gross, T., Giotopoulos, G., Beinortas, T., Navarro-Alonso, M., Aguado-Alvaro, L.P., Zazpe, J., Marchese, F., Torrea, N., Calvo, I.A., Lopez, C.K., Alignani, D., Lopez, A., Saez, B., Taylor-King, J.P., Prosper, F., Fortelny, N., and Huntly, B.J.P. (2023). In vivo screening characterizes chromatin factor functions during normal and malignant hematopoiesis. Nat. Genet. 55, 1542-1554. 10.1038/s41588-023-01471-2.

  • Krenn, P.W., and Aberger, F. (2023). Targeting cancer hallmark vulnerabilities in hematologic malignancies by interfering with Hedgehog/GLI signaling. Blood 142, 1945-1959. 10.1182/blood.2021014761.

  • Kiss, M.G., Papac-Milicevic, N., Porsch, F., Tsiantoulas, D., Hendrikx, T., Takaoka, M., Dinh, H.Q., Narzt, M.S., Goderle, L., Ozsvar-Kozma, M., Schuster, M., Fortelny, N., Hladik, A., Knapp, S., Gruber, F., Pickering, M.C., Bock, C., Swirski, F.K., Ley, K., Zernecke, A., Cochain, C., Kemper, C., Mallat, Z., and Binder, C.J. (2023). Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis. Immunity 56, 1809-1824 e1810. 10.1016/j.immuni.2023.06.026.

  • Jansko-Gadermeir, B., Leisch, M., Gassner, F.J., Zaborsky, N., Dillinger, T., Hutter, S., Risch, A., Melchardt, T., Egle, A., Drost, M., Larcher-Senn, J., Greil, R., and Pleyer, L. (2023). Myeloid NGS Analyses of Paired Samples from Bone Marrow and Peripheral Blood Yield Concordant Results: A Prospective Cohort Analysis of the AGMT Study Group. Cancers (Basel) 15. 10.3390/cancers15082305.

  • Heinig, L.C., Huth, E.V.M., Yan, K., Schumacher, N., Nawrocki, M., Lory, N.C., Bradtke, P., Bertram, T., Rattay, G., Schmid, J., Huber, S., Wiech, T., Schmidt-Arras, D., Rose-John, S., and Mittrucker, H.W. (2023). Cell-Autonomous Constitutive gp130 Signaling in T Cells Amplifies TH17 Cell Responses and Causes Severe Lung Inflammation. J. Immunol. 210, 1717-1727. 10.4049/jimmunol.2200461.

  • Frauenlob, T., Neuper, T., Regl, C., Schaepertoens, V., Unger, M.S., Oswald, A.L., Dang, H.H., Huber, C.G., Aberger, F., Wessler, S., and Horejs-Hoeck, J. (2023). Helicobacter pylori induces a novel form of innate immune memory via accumulation of NF-small ka, CyrillicB proteins. Front. Immunol. 14, 1290833. 10.3389/fimmu.2023.1290833.

  • Fetahu, I.S., Esser-Skala, W., Dnyansagar, R., Sindelar, S., Rifatbegovic, F., Bileck, A., Skos, L., Bozsaky, E., Lazic, D., Shaw, L., Totzl, M., Tarlungeanu, D., Bernkopf, M., Rados, M., Weninger, W., Tomazou, E.M., Bock, C., Gerner, C., Ladenstein, R., Farlik, M., Fortelny, N., and Taschner-Mandl, S. (2023). Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis. Nat Commun 14, 3620. 10.1038/s41467-023-39210-0.

  • Ettinger, M., Burner, T., Sharma, A., Chang, Y.T., Lackner, A., Prompsy, P., Deli, I.M., Traxler, J., Wahl, G., Altrichter, S., Langer, R., Tsai, Y.C., Varkhande, S.R., Schoeftner, L.C., Iselin, C., Gratz, I.K., Kimeswenger, S., Guenova, E., and Hoetzenecker, W. (2023). Th17-associated cytokines IL-17 and IL-23 in inflamed skin of Darier disease patients as potential therapeutic targets. Nat Commun 14, 7470. 10.1038/s41467-023-43210-5.

  • Esser-Skala, W., and Fortelny, N. (2023). Reliable interpretability of biology-inspired deep neural networks. NPJ Syst Biol Appl 9, 50. 10.1038/s41540-023-00310-8.

  • Du, M., Xin, J., Zheng, R., Yuan, Q., Wang, Z., Liu, H., Liu, H., Cai, G., Albanes, D., Lam, S., Tardon, A., Chen, C., Bojesen, S.E., Landi, M.T., Johansson, M., Risch, A., Bickeboller, H., Wichmann, H.E., Rennert, G., Arnold, S., Brennan, P., Field, J.K., Shete, S.S., Le Marchand, L., Liu, G., Andrew, A.S., Kiemeney, L.A., Zienolddiny, S., Grankvist, K., Johansson, M., Caporaso, N.E., Cox, A., Hong, Y.C., Yuan, J.M., Schabath, M.B., Aldrich, M.C., Wang, M., Shen, H., Chen, F., Zhang, Z., Hung, R.J., Amos, C.I., Wei, Q., Lazarus, P., and Christiani, D.C. (2023). CYP2A6 activity and cigarette consumption interact in smoking-related lung cancer susceptibility. Cancer Res. 10.1158/0008-5472.CAN-23-0900.

  • Chung, F.F., Maldonado, S.G., Nemc, A., Bouaoun, L., Cahais, V., Cuenin, C., Salle, A., Johnson, T., Erguner, B., Laplana, M., Datlinger, P., Jeschke, J., Weiderpass, E., Kristensen, V., Delaloge, S., Fuks, F., Risch, A., Ghantous, A., Plass, C., Bock, C., Kaaks, R., and Herceg, Z. (2023). Buffy coat signatures of breast cancer risk in a prospective cohort study. Clin. Epigenetics 15, 102. 10.1186/s13148-023-01509-6.

  • Cheng, C., Hong, W., Li, Y., Xiao, X., McKay, J., Han, Y., Byun, J., Peng, B., Albanes, D., Lam, S., Tardon, A., Chen, C., Bojesen, S.E., Landi, M.T., Johansson, M., Risch, A., Bickeboller, H., Wichmann, H.E., Christiani, D.C., Rennert, G., Arnold, S., Goodman, G., Field, J.K., Davies, M.P.A., Shete, S.S., Le Marchand, L., Liu, G., Hung, R.J., Andrew, A.S., Kiemeney, L.A., Zhu, M., Shen, H., Zienolddiny, S., Grankvist, K., Johansson, M., Cox, A., Hong, Y.C., Yuan, J.M., Lazarus, P., Schabath, M.B., Aldrich, M.C., Brennan, P., Li, Y., Gorlova, O., Gorlov, I., Amos, C.I., and Consortium, I.-I.L.C. (2023). Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis. J. Thorac. Oncol. 18, 1003-1016. 10.1016/j.jtho.2023.05.001.

  • Chen, Y.H., van Zon, S., Adams, A., Schmidt-Arras, D., Laurence, A.D.J., and Uhlig, H.H. (2023). The Human GP130 Cytokine Receptor and Its Expression-an Atlas and Functional Taxonomy of Genetic Variants. J. Clin. Immunol. 44, 30. 10.1007/s10875-023-01603-7.

  • C, A.M., Wessler, S., and Ponnuraj, K. (2023). Inhibition of Listeria Monocytogenes HtrA Protease with Camostat, Gabexate and Nafamostat Mesylates and the Binding Mode of the Inhibitors. The protein journal 42, 343-354. 10.1007/s10930-023-10114-8.

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