CCS Publications  2021

Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeboller H, Bojesen SE, Brennan P, Brunnstrom H, Melander O, Caporaso NE, Landi MT, Chen C, Goodman GE, Christiani DC, Cox A, Field JK, Johansson M, Kiemeney LA, Lam S, Lazarus P, Le Marchand L, Rennert G, Risch A, Schabath MB, Shete SS, Tardon A, Zienolddiny S, Shen H, Amos CI: Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization. Int J Cancer 2021, 148:1077-1086.

Yu X, Munoz-Sagredo L, Streule K, Muschong P, Bayer E, Walter RJ, Gutjahr JC, Greil R, Concha ML, Muller-Tidow C, Hartmann TN, Orian-Rousseau V: CD44 loss of function sensitizes AML cells to the BCL-2 inhibitor venetoclax by decreasing CXCL12-driven survival cues. Blood 2021, 138:1067-1080.

Wulf GG, Altmann B, Ziepert M, D'Amore F, Held G, Greil R, Tournilhac O, Relander T, Viardot A, Wilhelm M, Wilhelm C, Pezzutto A, Zijlstra JM, Neste EVD, Lugtenburg PJ, Doorduijn JK, Gelder MV, van Imhoff GW, Zettl F, Braulke F, Nickelsen M, Glass B, Rosenwald A, Gaulard P, Loeffler M, Pfreundschuh M, Schmitz N, Trumper L, investigators ACTs: Alemtuzumab plus CHOP versus CHOP in elderly patients with peripheral T-cell lymphoma: the DSHNHL2006-1B/ACT-2 trial. Leukemia 2021, 35:143-155.

Wierda WG, Rawstron A, Cymbalista F, Badoux X, Rossi D, Brown JR, Egle A, Abello V, Cervera Ceballos E, Herishanu Y, Mulligan SP, Niemann CU, Diong CP, Soysal T, Suzuki R, Tran HTT, Wu SJ, Owen C, Stilgenbauer S, Ghia P, Hillmen P: Measurable residual disease in chronic lymphocytic leukemia: expert review and consensus recommendations. Leukemia 2021.

Westphal T, Gampenrieder SP, Rinnerthaler G, Balic M, Posch F, Dandachi N, Hauser-Kronberger C, Reitsamer R, Sotlar K, Radl B, Suppan C, Stoger H, Greil R: Transferring MINDACT to Daily Routine: Implementation of the 70-Gene Signature in Luminal Early Breast Cancer - Results from a Prospective Registry of the Austrian Group Medical Tumor Therapy (AGMT). Breast Care 2021.

von Heydebrand F, Fuchs M, Kunz M, Voelkl S, Kremer AN, Oostendorp RAJ, Wilke J, Leitges M, Egle A, Mackensen A, Lutzny-Geier G: Protein kinase C-beta-dependent changes in the glucose metabolism of bone marrow stromal cells of chronic lymphocytic leukemia. Stem Cells 2021, 39:819-830.

Urwanisch L, Luciano M, Horejs-Hoeck J: The NLRP3 Inflammasome and Its Role in the Pathogenicity of Leukemia. Int J Mol Sci 2021, 22.

Tripolt S, Neubauer HA, Knab VM, Elmer DP, Aberger F, Moriggl R, Fux DA: Opioids drive breast cancer metastasis through the delta-opioid receptor and oncogenic STAT3. Neoplasia 2021, 23:270-279.

Swoboda A, Soukup R, Eckel O, Kinslechner K, Wingelhofer B, Schorghofer D, Sternberg C, Pham HTT, Vallianou M, Horvath J, Stoiber D, Kenner L, Larue L, Poli V, Beermann F, Yokota T, Kubicek S, Krausgruber T, Rendeiro AF, Bock C, Zenz R, Kovacic B, Aberger F, Hengstschlager M, Petzelbauer P, Mikula M, Moriggl R: STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway. Oncogene 2021, 40:1091-1105.

Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bosse Y, Lam S, Tsao MS, Tardon A, Chen C, Doherty J, Goodman G, Bojesen SE, Landi MT, Johansson M, Field JK, Bickeboller H, Wichmann HE, Risch A, Rennert G, Arnold S, Wu X, Melander O, Brunnstrom H, Le Marchand L, Liu G, Andrew A, Duell E, Kiemeney LA, Shen H, Haugen A, Johansson M, Grankvist K, Caporaso N, Woll P, Dawn Teare M, Scelo G, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Albanes D, Mak R, Barbie D, Brennan P, Hung RJ, Amos CI, Christiani DC, Lin X: Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer. Genet Epidemiol 2021, 45:99-114.

Steiner M, Gassner FJ, Parigger T, Neureiter D, Egle A, Geisberger R, Greil R, Zaborsky N: A POLE Splice Site Deletion Detected in a Patient with Biclonal CLL and Prostate Cancer: A Case Report. Int J Mol Sci 2021, 22.

Schubert M, Gassner FJ, Huemer M, Hopner JP, Akimova E, Steiner M, Egle A, Greil R, Zaborsky N, Geisberger R: AID Contributes to Accelerated Disease Progression in the TCL1 Mouse Transplant Model for CLL. Cancers (Basel) 2021, 13.

Schlintl V, Huemer F, Greil R, Weiss L: Ramucirumab plus FOLFIRI or irinotecan as second-line therapy in advanced or metastatic gastric or gastroesophageal junction adenocarcinoma. J Gastrointest Oncol 2021, 12:906-909.

Schlick K, Markus S, Huemer F, Ratzinger L, Zaborsky N, Clemens H, Neureiter D, Neumayer B, Beate AS, Florian S, Martin V, Grundbichler M, Weiss L, Melchardt T, Greil R, Egle A: Evaluation of circulating cell-free KRAS mutational status as a molecular monitoring tool in patients with pancreatic cancer. Pancreatology 2021.

Schamschula E, Lahnsteiner A, Assenov Y, Hagmann W, Zaborsky N, Wiederstein M, Strobl A, Stanke F, Muley T, Plass C, Tummler B, Risch A: Disease-related blood-based differential methylation in cystic fibrosis and its representation in lung cancer revealed a regulatory locus in PKP3 in lung epithelial cells. Epigenetics 2021:1-24.

Schamschula E, Hagmann W, Assenov Y, Hedtfeld S, Farag AK, Roesner LM, Wiehlmann L, Stanke F, Fischer S, Risch A, Tummler B: Immunotyping of clinically divergent p.Phe508del homozygous monozygous cystic fibrosis twins. J Cyst Fibros 2021, 20:149-153.

Rinnerthaler G, Muller V, Balic M, Zaman K, Dieci MV: Expert Discussion: Immunotherapy in Breast Cancer - Ready for Prime Time? Breast Care (Basel) 2021, 16:188-191.

Rinnerthaler G, Gampenrieder SP, Tinchon C, Petzer AL, Suppan C, Heibl S, Voskova D, Zabernigg AF, Egle D, Sandholzer M, Singer CF, Roitner F, Andel J, Hubalek M, Knauer M, Greil R: First-line treatment of hormone receptor positive metastatic breast cancer (MBC) in everyday practice: Results from the Austrian AGMT_MBC-Registry. Cancer Research 2021, 81.

Rauscher S, Greil R, Geisberger R: Re-Sensitizing Tumor Cells to Cancer Drugs with Epigenetic Regulators. Curr Cancer Drug Targets 2021, 21:353-359.

Qin N, Li Y, Wang C, Zhu M, Dai J, Hong T, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojesen SE, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeboller H, Rennert G, Arnold S, Brennan P, Field JK, Shete S, Le Marchand L, Melander O, Brunnstrom H, Liu G, Hung RJ, Andrew A, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Woll P, Lazarus P, Schabath MB, Aldrich MC, Stevens VL, Jin G, Christiani DC, Hu Z, Amos CI, Ma H, Shen H: Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Front Med 2021, 15:275-291.

Pleyer L, Leisch M, Kourakli A, Padron E, Maciejewski JP, Xicoy Cirici B, Kaivers J, Ungerstedt J, Heibl S, Patiou P, Hunter AM, Mora E, Geissler K, Dimou M, Jimenez Lorenzo MJ, Melchardt T, Egle A, Viniou AN, Patel BJ, Arnan M, Valent P, Roubakis C, Bernal Del Castillo T, Galanopoulos A, Calabuig Munoz M, Bonadies N, Medina de Almeida A, Cermak J, Jerez A, Montoro MJ, Cortes A, Avendano Pita A, Lopez Andrade B, Hellstroem-Lindberg E, Germing U, Sekeres MA, List AF, Symeonidis A, Sanz GF, Larcher-Senn J, Greil R: Outcomes of patients with chronic myelomonocytic leukaemia treated with non-curative therapies: a retrospective cohort study. Lancet Haematol 2021, 8:e135-e148.

Peer E, Aichberger SK, Vilotic F, Gruber W, Parigger T, Grund-Groschke S, Elmer DP, Rathje F, Ramspacher A, Zaja M, Michel S, Hamm S, Aberger F: Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog-GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition. Cancers (Basel) 2021, 13:2021.2006.2017.448773.

Parigger T, Gassner FJ, Scherhaufl C, Bakar AA, Hopner JP, Hodlmoser A, Steiner M, Catakovic K, Geisberger R, Greil R, Zaborsky N: Evidence for Non-Cancer-Specific T Cell Exhaustion in the Tcl1 Mouse Model for Chronic Lymphocytic Leukemia. Int J Mol Sci 2021, 22.

Orfanoudaki M, Hartmann A, Alilou M, Mehic N, Kwiatkowski M, Johrer K, Nguyen Ngoc H, Hensel A, Greil R, Ganzera M: Cytotoxic Compounds of Two Demosponges (Aplysina aerophoba and Spongia sp.) from the Aegean Sea. Biomolecules 2021, 11.

Neuper T, Neureiter D, Sarajlic M, Strandt H, Bauer R, Schwarz H, Suchanek P, Korotchenko E, Dillon SR, Hammerl P, Stoecklinger A, Weiss R, Horejs-Hoeck J: IL-31 transgenic mice show reduced allergen-induced lung inflammation. Eur J Immunol 2021, 51:191-196.

Michelini S, Barbero F, Prinelli A, Steiner P, Weiss R, Verwanger T, Andosch A, Lutz-Meindl U, Puntes VF, Drobne D, Duschl A, Horejs-Hoeck J: Gold nanoparticles (AuNPs) impair LPS-driven immune responses by promoting a tolerogenic-like dendritic cell phenotype with altered endosomal structures. Nanoscale 2021, 13:7648-7666.

Magnes T, Wagner SM, Melchardt T, Weiss L, Rinnerthaler G, Huemer F, Kopp M, Gampenrieder SP, Mayrbaurl B, Fureder T, Lenger D, Andel J, Egle A, Greil R: Postoperative chemoradiotherapy with cisplatin is superior to radioimmunotherapy with cetuximab and radiotherapy alone : Analysis of the Austrian head and neck cancer registry of the AGMT. Wien Klin Wochenschr 2021.

Magnes T, Wagner S, Thorner AR, Neureiter D, Klieser E, Rinnerthaler G, Weiss L, Huemer F, Zaborsky N, Steiner M, Weis S, Greil R, Egle A, Melchardt T: Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence. ESMO Open 2021, 6:100012.

Magnes T, Wagner S, Thorner AR, Neureiter D, Klieser E, Rinnerthaler G, Weiss L, Huemer F, Schlick K, Zaborsky N, Steiner M, Greil R, Egle A, Melchardt T: Spatial Heterogeneity in Large Resected Diffuse Large B-Cell Lymphoma Bulks Analysed by Massively Parallel Sequencing of Multiple Synchronous Biopsies. Cancers (Basel) 2021, 13.

Magnes T, Wagner S, Kiem D, Weiss L, Rinnerthaler G, Greil R, Melchardt T: Prognostic and Predictive Factors in Advanced Head and Neck Squamous Cell Carcinoma. Int J Mol Sci 2021, 22.

Luciano M, Blöchl C, Vetter J, Urwanisch L, Neuper T, Elmer DP, Bauer R, Dang H-H, Strandt H, Neureiter D, Krenn P, Tesanovic S, Rieser S, Bergsleitner O, Zell L, Binder S, Schaller S, Strunk D, Pleyer L, Greil R, Winkler S, Hartmann TN, Huber CG, Aberger F, Horejs-Hoeck J: The NLRP3/eIF2 axis drives cell cycle progression in acute myeloid leukemia. bioRxiv 2021:2021.2006.2025.449862.

Lesseur C, Ferreiro-Iglesias A, McKay JD, Bosse Y, Johansson M, Gaborieau V, Landi MT, Christiani DC, Caporaso NC, Bojesen SE, Amos CI, Shete S, Liu G, Rennert G, Albanes D, Aldrich MC, Tardon A, Chen C, Triantafillos L, Field JK, Teare MD, Kiemeney LA, Diergaarde B, Ferris RL, Zienolddiny S, Lam S, Olshan AF, Weissler MC, Lacko M, Risch A, Bickeboller H, Ness AR, Thomas S, Le Marchand L, Schabath MB, Wunsch-Filho V, Tajara EH, Andrew AS, Clifford GM, Lazarus P, Grankvist K, Johansson M, Arnold S, Melander O, Brunnstrom H, Boccia S, Cadoni G, Timens W, Obeidat M, Xiao X, Houlston RS, Hung RJ, Brennan P: Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. PLoS Genet 2021, 17:e1009254.

Lebede M, Di Marco F, Esser-Skala W, Hennig R, Wohlschlager T, Huber CG: Exploring the Chemical Space of Protein Glycosylation in Noncovalent Protein Complexes: An Expedition along Different Structural Levels of Human Chorionic Gonadotropin by Employing Mass Spectrometry. Anal Chem 2021, 93:10424-10434.

Laplana M, Bieg M, Faltus C, Melnik S, Bogatyrova O, Gu Z, Muley T, Meister M, Dienemann H, Herpel E, Amos CI, Schlesner M, Eils R, Plass C, Risch A: Differentially methylated regions within lung cancer risk loci are enriched in deregulated enhancers. Epigenetics 2021:1-16.

Kwik M, Hainzl S, Oppelt J, Tichy B, Koller U, Bernardinelli E, Steiner M, Zara G, Nofziger C, Weis S, Paulmichl M, Dossena S, Patsch W, Soyal SM: Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases. Int J Mol Sci 2021, 22.

Korotchenko E, Schiessl V, Scheiblhofer S, Schubert M, Dall E, Joubert IA, Strandt H, Neuper T, Sarajlic M, Bauer R, Geppert M, Joedicke D, Wildner S, Schaller S, Winkler S, Gadermaier G, Horejs-Hoeck J, Weiss R: Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in a mouse model of allergic asthma. Allergy 2021, 76:210-222.

Kocher F, Tymoszuk P, Amann A, Sprung S, Salcher S, Daum S, Haybaeck J, Rinnerthaler G, Huemer F, Kauffmann-Guerrero D, Tufman A, Seeber A, Wolf D, Pircher A: Deregulated glutamate to pro-collagen conversion is associated with adverse outcome in lung cancer and may be targeted by renin-angiotensin-aldosterone system (RAS) inhibition. Lung Cancer 2021, 159:84-95.

Kiem D, Leisch M, Neureiter D, Haslauer T, Egle A, Melchardt T, Topp MS, Greil R: Two Cases of Pancytopenia with Coombs-Negative Hemolytic Anemia after Chimeric Antigen Receptor T-Cell Therapy. Int J Mol Sci 2021, 22.

Keil F, Hartl M, Altorjai G, Berghold A, Riedl R, Pecherstorfer M, Mayrbaurl B, De Vries A, Schuster J, Hackl J, Fureder T, Melchardt T, Burian M, Greil R: Docetaxel, cisplatin and 5-FU compared with docetaxel, cisplatin and cetuximab as induction chemotherapy in advanced squamous cell carcinoma of the head and neck: Results of a randomised phase II AGMT trial. Eur J Cancer 2021, 151:201-210.

Hung RJ, Warkentin MT, Brhane Y, Chatterjee N, Christiani DC, Landi MT, Caporaso NE, Liu G, Johansson M, Albanes D, Marchand LL, Tardon A, Rennert G, Bojesen SE, Chen C, Field JK, Kiemeney LA, Lazarus P, Zienolddiny S, Lam S, Andrew AS, Arnold SM, Aldrich MC, Bickeboller H, Risch A, Schabath MB, McKay JD, Brennan P, Amos CI: Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model. Cancer Res 2021, 81:1607-1615.

Huemer F, Rinnerthaler G, Jorg B, Morre P, Stegbuchner B, Proksch E, Fleimisch S, Oberkofler H, Kremser I, Greil R, Egle A: Results of a hospitalization policy of asymptomatic and pre-symptomatic COVID-19-positive long-term care facility residents in the province of Salzburg-a report from the AGMT COVID-19 Registry. Geroscience 2021.

Huemer F, Leisch M, Geisberger R, Zaborsky N, Greil R: miRNA-Based Therapeutics in the Era of Immune-Checkpoint Inhibitors. Pharmaceuticals (Basel) 2021, 14.

Hinterholzer A, Stanojlovic V, Regl C, Huber CG, Cabrele C, Schubert M: Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy. J Biomol NMR 2021, 75:71-82.

Heregger R, Huemer F, Hutarew G, Hecht S, Cheveresan L, Kotzot D, Schamschula E, Rinnerthaler G, Melchardt T, Weiss L, Greil R: Sustained response to brigatinib in a patient with refractory metastatic pheochromocytoma harboring R1192P anaplastic lymphoma kinase mutation: a case report from the Austrian Group Medical Tumor Therapy next-generation sequencing registry and discussion of the literature. ESMO Open 2021, 6:100233.

Hecht JR, Lonardi S, Bendell J, Sim HW, Macarulla T, Lopez CD, Van Cutsem E, Munoz Martin AJ, Park JO, Greil R, Wang H, Hozak RR, Gueorguieva I, Lin Y, Rao S, Ryoo BY: Randomized Phase III Study of FOLFOX Alone or With Pegilodecakin as Second-Line Therapy in Patients With Metastatic Pancreatic Cancer That Progressed After Gemcitabine (SEQUOIA). J Clin Oncol 2021, 39:1108-1118.

Hatzl S, Posch F, Rezai A, Gornicec M, Beham-Schmid C, Magnes T, Wangner S, Deutsch A, Greinix H, Uhl B, Prochazka KT, Egle A, Greil R, Melchardt T, Linkesch W, Schulz E, Neumeister P: Vinorelbine as substitute for vincristine in patients with diffuse large B cell lymphoma and vincristine-induced neuropathy. Support Care Cancer 2021, 29:5197-5207.

Haslauer T, Greil R, Zaborsky N, Geisberger R: CAR T-Cell Therapy in Hematological Malignancies. Int J Mol Sci 2021, 22.

Gutjahr JC, Bayer E, Yu X, Laufer JM, Hopner JP, Tesanovic S, Harzschel A, Auer G, Riess T, Salmhofer A, Szenes E, Haslauer T, Durand-Onayli V, Ramspacher A, Pennisi SP, Artinger M, Zaborsky N, Chigaev A, Aberger F, Neureiter D, Pleyer L, Legler DF, Orian-Rousseau V, Greil R, Hartmann TN: CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity. Haematologica 2021, 106:2102-2113.

Greil R, Tedeschi A, Moreno C, Anz B, Larratt L, Simkovic M, Gill D, Gribben JG, Flinn IW, Wang Z, Cheung LWK, Nguyen AN, Zhou C, Styles L, Demirkan F: Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL: analysis from the iLLUMINATE study. Ann Hematol 2021, 100:1733-1742.

Gnant M, Fitzal F, Rinnerthaler G, Steger GG, Greil-Ressler S, Balic M, Heck D, Jakesz R, Thaler J, Egle D, Manfreda D, Bjelic-Radisic V, Wieder U, Singer CF, Melbinger-Zeinitzer E, Haslbauer F, Sevelda P, Trapl H, Wette V, Wimmer K, Gampenrieder SP, Bartsch R, Kacerovsky-Strobl S, Suppan C, Brunner C, Deutschmann C, Soelkner L, Fesl C, Greil R, Austrian B, Colorectal Cancer Study G: Duration of Adjuvant Aromatase-Inhibitor Therapy in Postmenopausal Breast Cancer. N Engl J Med 2021, 385:395-405.

Gassner FJ, Zaborsky N, Buchumenski I, Levanon EY, Gatterbauer M, Schubert M, Rauscher S, Hebenstreit D, Nadeu F, Campo E, Egle A, Greil R, Geisberger R: RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia. Leukemia 2021, 35:1053-1063.

Gampenrieder SP, Rinnerthaler G, Tinchon C, Petzer AL, Suppan C, Heibl S, Voskova D, Zabernigg AF, Egle D, Sandholzer M, Singer CF, Roitner F, Andel J, Hubalek M, Knauer M, Greil R: Does complete surgical removal of metastases in oligometastatic breast cancer improve survival? A matched-pair analysis of the AGMT_MBC-registry. Cancer Research 2021, 81.

Gampenrieder SP, Pircher M, Fesl C, Rinnerthaler G, Mlineritsch B, Greil-Ressler S, Steger GG, Sagaster V, Fitzal F, Exner R, Devyatko Y, Balic M, Stoger H, Suppan C, Bauernhofer T, Singer CF, Pfeiler G, Seifert M, Helfgott R, Heck D, Rumpold H, Kwasny W, Wieder U, Gnant M, Greil R, St ABCC: Influence of Height on Risk and Outcome of Patients with Early Breast Cancer: A Pooled Analysis of 4,925 Patients from 5 Randomized Trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG). Breast Care 2021.

Ferstl FS, Gampenrieder SP, Renneberg F, Roesch S: Dysphagia in the Context of a Serious Systemic Disease. Dysphagia 2021, 36:497-499.

Dubsky P, Van't Veer L, Gnant M, Rudas M, Bago-Horvath Z, Greil R, Lujinovic E, Buresch J, Rinnerthaler G, Hulla W, Moinfar F, Egle D, Herz W, Dreezen C, Frantal S, Filipits M: A clinical validation study of MammaPrint in hormone receptor-positive breast cancer from the Austrian Breast and Colorectal Cancer Study Group 8 (ABCSG-8) biomarker cohort. ESMO Open 2021, 6:100006.

Cicek SS, Willer J, Preziuso F, Sonnichsen F, Greil R, Girreser U, Zidorn C, Johrer K: Cytotoxic constituents and a new hydroxycinnamic acid derivative from Leontodon saxatilis (Asteraceae, Cichorieae). Rsc Advances 2021, 11:10489-10496.

Buxhofer-Ausch V, Heibl S, Sliwa T, Beham-Schmid C, Wolf D, Geissler K, Krauth MT, Krippl P, Petzer A, Wolfler A, Melchardt T, Gisslinger H: Austrian recommendations for the management of essential thrombocythemia. Wien Klin Wochenschr 2021, 133:52-61.

Breunig S, Wallner V, Kobler K, Wimmer H, Steinbacher P, Streubel MK, Bischof J, Duschl J, Neuhofer C, Gruber W, Aberger F, Breitenbach M, Russe E, Wechselberger G, Duranton A, Richter K, Rinnerthaler M: The life in a gradient: calcium, the lncRNA SPRR2C and mir542/mir196a meet in the epidermis to regulate the aging process. Aging (Albany NY) 2021, 13:19127-19144.

Bernard S, Ghesquieres H, Casasnovas RO, Griolet S, Gomes da Silva M, Feugier P, Morschhauser F, Trotman J, Renaud L, Greil R, Garcia-Sancho AM, Grosicki S, van Eygen K, Copie-Bergman C, Haioun C, Thieblemont C: Incidence of central nervous system relapses in patients with DLBCL treated with lenalidomide as maintenance after R-CHOP. Blood Adv 2021, 5:2965-2968.

Bauer J, Cuvelier N, Ragab N, Simon-Keller K, Nitzki F, Geyer N, Botermann DS, Elmer DP, Rosenberger A, Rando TA, Biressi S, Fagin JA, Saur D, Dullin C, Schildhaus HU, Schulz-Schaeffer W, Aberger F, Uhmann A, Hahn H: Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms. Oncogene 2021, 40:4955-4966.

Bartsch R, Singer CF, Pfeiler G, Hubalek M, Stoeger H, Pichler A, Petru E, Bjelic-Radisic V, Greil R, Rudas M, Muy-Kheng TM, Wette V, Petzer AL, Sevelda P, Egle D, Dubsky PC, Filipits M, Fitzal F, Exner R, Jakesz R, Balic M, Tinchon C, Bago-Horvath Z, Frantal S, Gnant M, Austrian B, Colorectal Cancer Study G: Conventional versus reverse sequence of neoadjuvant epirubicin/cyclophosphamide and docetaxel: sequencing results from ABCSG-34. Br J Cancer 2021, 124:1795-1802.

Akimova E, Gassner FJ, Schubert M, Rebhandl S, Arzt C, Rauscher S, Tober V, Zaborsky N, Greil R, Geisberger R: SAMHD1 restrains aberrant nucleotide insertions at repair junctions generated by DNA end joining. Nucleic Acids Res 2021, 49:2598-2608.

Aftimos P, Oliveira M, Irrthum A, Fumagalli D, Sotiriou C, Nili Gal-Yam E, Robson ME, Ndozeng J, Di Leo A, Ciruelos EM, de Azambuja E, Viale G, Scheepers ED, Curigliano G, Bliss JM, Reis-Filho JS, Colleoni M, Balic M, Cardoso F, Albanell J, Duhem C, Marreaud S, Romagnoli D, Rojas B, Gombos A, Wildiers H, Guerrero-Zotano A, Hall P, Bonetti A, Larsson KF, Degiorgis M, Khodaverdi S, Greil R, Sverrisdottir A, Paoli M, Seyll E, Loibl S, Linderholm B, Zoppoli G, Davidson NE, Johannsson OT, Bedard PL, Loi S, Knox S, Cameron DA, Harbeck N, Lasa Montoya M, Brandao M, Vingiani A, Caballero C, Hilbers FS, Yates LR, Benelli M, Venet D, Piccart MJ: Genomic and transcriptomic analyses of breast cancer primaries and matched metastases in AURORA, the Breast International Group (BIG) molecular screening initiative. Cancer Discov 2021.